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The Pharma Closeout | Daily Pharmaceutical & Biotech News in 15 minus The Pharma Closeout | Daily Pharmaceutical & Biotech News in 15 minus BZ Group Delving In with Stuart Kelter Delving In with Stuart Kelter Stuart Kelter The Deep-Sea Podcast The Deep-Sea Podcast Thomas Linley TED-Ed TED-Ed TED-Ed God's Eye View God's Eye View Trevor The Poison Lab The Poison Lab Clinical Toxicology LLC 絮言.狂想 seoijin 絮言.狂想 seoijin 以色列、三苗、靳尼 Tommy Cullum's Let's Get Freaky Tommy Cullum's Let's Get Freaky Tommy Cullum The Relational Social Work Podcast The Relational Social Work Podcast Matt and Hannah GU Cast | Urology Podcast GU Cast | Urology Podcast Professor Declan Murphy & Dr Renu Eapen Designing Healthcare that Cares Podcast Designing Healthcare that Cares Podcast Doctor Podcast Network, Dr. Laura Suttin Thrilling Threads - Conspiracy Theories, Strange Phenomena, True Crime, Unsolved Mysteries, etc! Thrilling Threads - Conspiracy Theories, Strange Phenomena, True Crime, Unsolved Mysteries, etc! Byte & Pieces PBS Space Time PBS Space Time PBS Almanacco del giorno Almanacco del giorno Streammo Slick Slime Sam Slick Slime Sam TheSoul Publishing Hillbilly Horror Stories Paranormal Podcast Hillbilly Horror Stories Paranormal Podcast Jerry Paulley ReddX Reddit Reads ReddX Reddit Reads ReddX Arroe Collins Forest Stories Arroe Collins Forest Stories Arroe Collins The GMP Insider The GMP Insider Tushar Arora Two Money Lovers  經濟學不是萬能但有用 Two Money Lovers 經濟學不是萬能但有用 季凡 & 翔蛇 Matt From Nomad’s Matt From Nomad’s Matt Crabtree The Political Cesspool Radio Show Podcast Feed The Political Cesspool Radio Show Podcast Feed James Edwards Next-gen Hills Naturalists Next-gen Hills Naturalists Coen and Eve The Christian Mind Reset The Christian Mind Reset The Christian Mind Reset Maintenant Vous Savez Santé Maintenant Vous Savez Santé Bababam Vedanta Cast Vedanta Cast Jonas Masetti Soif de Sens | Écologie & social Soif de Sens | Écologie & social Pierre Chevelle | Écologie London Weather Daily London Weather Daily Fast Foundations Talking Rubbish - Recycled Content Talking Rubbish - Recycled Content James Piper, Robbie Staniforth EXTRA ANORMAL EXTRA ANORMAL iEX Studios The Medbullets Step 2 & 3 Podcast The Medbullets Step 2 & 3 Podcast Medbullets Exploring Humanity Through Sci-Fi Exploring Humanity Through Sci-Fi Tony Tellado De Universiteit van Nederland Podcast De Universiteit van Nederland Podcast Universiteit van Nederland The Future Conceived The Future Conceived SSR Podcast On This Day in Working Class History On This Day in Working Class History Working Class History Geladen - der Batteriepodcast zur Energiewende Geladen - der Batteriepodcast zur Energiewende Daniel Messling, Patrick von Rosen JP Lovecraft's Creepy Podcast JP Lovecraft's Creepy Podcast JP Lovecraft
The Pharma Closeout | Daily Pharmaceutical & Biotech News in 15 minus

Ciencia

The Pharma Closeout | Daily Pharmaceutical & Biotech News in 15 minus

BZ Group

Jun 26, 2026 | FDA Approves Viridian for Thyroid Eye Disease; Merck KGaA's $11.3B Bio-Techne Deal

June 27, 2026 5:50pm 14 min

FDA breaks Amgen's Tepezza monopoly with Viridian's Lumvoa approval in thyroid eye disease. Plus Merck KGaA's $11.3B Bio-Techne acquisition, Biogen gutting the Apellis pipeline post-$5.6B deal, CHMP moves to revoke Tavne...

Jun 25, 2026 | Ionis Tryngolza FDA Label Expansion Hits Commercial Inflection

June 26, 2026 2:14am 9 min

FDA approves Ionis Tryngolza as first treatment to reduce pancreatitis risk in severe hypertriglyceridemia — a potential blockbuster expansion. Merck KGaA acquires Bio-Techne for $11.3B in largest deal in a decade. SCOTU...

Jun 24, 2026 | FDA Approves Gilead's Trodelvy for Front-Line TNBC; Lilly's $1.9B Abbisko Deal

June 25, 2026 12:04am 13 min

Gilead's Trodelvy wins front-line triple-negative breast cancer approval — and the stock barely moves. Lilly expands its Abbisko partnership to $1.9B, Novartis pays $105M upfront to Antares for undruggable cancer targets...

Jun 23, 2026 | Pfizer Seagen ADC Fails in Lung Cancer Phase 3; CMS Settles Opzelura Classification

June 23, 2026 9:19pm 14 min

Pfizer's sigvotatug vedotin disappoints in Phase 3 NSCLC — another blow to the $43B Seagen deal. Plus CMS settles with Incyte on Opzelura classification, Sangamo Therapeutics closes after 30 years, and Moderna's flu vacc...

Jun 22, 2026 | AbbVie's $10.9B Apogee Buy Targets Dupixent; 1st Solid Tumor CAR-T Approved in China

June 22, 2026 9:18pm 10 min

AbbVie bets $10.9B on Apogee Therapeutics to challenge Dupixent — its biggest deal since Allergan. Plus: the first CAR-T approved for a solid tumor clears in China, Merck's $10.8B Prometheus IBD bet pays off with a Phase...

Jun 19, 2026 | US Probes Germany Drug Pricing; Moderna Flu Vaccine Wins Unanimous FDA Panel

June 20, 2026 2:01am 10 min

US government opens formal probe into Germany's drug pricing reforms, escalating transatlantic pharma trade tensions. Kardigan IPO raises $400M and pops 31%. Moderna flu vaccine gets unanimous FDA advisory panel support ...

Jun 18, 2026 | Moderna mFlusiva Wins Unanimous VRBPAC Vote; NovoCure TRIDENT Fails in GBM

June 18, 2026 8:50pm 13 min

Moderna's mRNA flu vaccine gets unanimous FDA panel backing — PDUFA August 5. NovoCure's TRIDENT trial misses overall survival in glioblastoma; stock drops ~18%. Biogen acquires immunology startup RayThera for up to $1B;...

Jun 17, 2026 | UniQure AMT-130 Surges 70% on FDA Reversal; Jazz-AbCellera $4.1B TCE Deal

June 17, 2026 9:17pm 14 min

UniQure surges 70% as FDA reverses course on Huntington's gene therapy AMT-130 filing path. Jazz and AbCellera strike $4.1B T cell engager deal for GI cancers. Novo Nordisk faces $25M ransom demand after hackers claim dr...

Jun 16, 2026 | BridgeBio BBP-418 Sweeps LGMD Phase 3; FDA Scrutinizes Moderna Flu Vaccine

June 17, 2026 7:30am 10 min

BridgeBio's BBP-418 sweeps Phase 3 in limb-girdle muscular dystrophy — stock up 15%, no approved competition. FDA briefing docs challenge Moderna mFlusiva efficacy ahead of Thursday's VRBPAC vote. Plus Lilly acquires non...

Jun 15, 2026 | CMS Targets SubQ Keytruda and Opdivo Loophole; Takeda Beats Sotyktu Head-to-Head

June 15, 2026 11:24pm 10 min

CMS proposes closing Medicare negotiation loophole threatening Keytruda and Opdivo subcutaneous strategies — billions at stake. Plus Takeda's zasocitinib tops Sotyktu, Novartis validates $12B Avidity deal, Elicio's KRAS ...

EHA 2026 Special — Full Meeting Recap

June 14, 2026 11:59pm 20 min

The Pharma Closeout's comprehensive recap of EHA 2026(Stockholm, June 11-14). HEADLINE: J&J's MonumenTAL-3 (talquetamab +daratumumab) in earlier-line R/R myeloma — PFS HR 0.28/0.33, complete-response 71% vs 34.5%, NEJM-p...

Jun 12, 2026 | FDA Approves Merck Welireg-Keytruda for Kidney Cancer; Jazz Zepzelca Phase 3 Fails

June 12, 2026 10:29pm 13 min

FDA approves Merck's Welireg-Keytruda combo for adjuvant kidney cancer — 28% risk reduction vs. active Keytruda monotherapy in LITESPARK-022. Jazz's Zepzelca misses OS endpoint in Phase 3 LAGOON, Incyte acquires Vega The...

Jun 11, 2026 | Takeda Zasocitinib Beats Sotyktu in Head-to-Head Phase 3; Summit Pulls $500M Offering

June 12, 2026 9:22am 10 min

Zasocitinib hits 35% complete skin clearance at week 16,topping Sotyktu by more than 2.5x in Takeda's head-to-head Phase 3. Plus: Novartis validates its $12B Avidity AOC platform in FSHD, Summit withdraws $500M offering,...

Jun 10, 2026 | Parabilis Sets Record $670M Biotech IPO; Sanofi Halts Riliprubart Phase 3

June 11, 2026 4:20pm 9 min

Parabilis Medicines prices the largest-ever venture-backed biotech IPO at $670M as 12 startups top $4.1B in 2026. Sanofi stops MOBILIZE Phase 3 for riliprubart in CIDP. TG Therapeutics surges on Briumvi myasthenia gravis...

ADA 2026 Special: The full recap

June 11, 2026 4:19pm 25 min

The Pharma Closeout's full recap of the American Diabetes Association's 86th Scientific Sessions (New Orleans,June 5-8, 2026) - the meeting that ended the A1C-only era and reset what obesity medicine can do. Hosts Alex M...

The AI Vendor Draft — How Big Pharma Picked Its AI Partners | The Pharma Closeout Special Report

June 08, 2026 3:43pm 18 min

In about six weeks this spring, four of the biggest names in pharma each picked an AI partner — Bristol Myers Squibb chose Anthropic's Claude for 30,000+ employees, Merck signed with Google Cloud for up to $1B, Novo Nord...

Jun 07, 2026 | Alnylam's $2B AI-RNA Deal with Inceptive; Lundbeck Bocunebart Migraine Data

June 08, 2026 8:10am 11 min

Alnylam commits up to $2B to Inceptive Nucleics forAI-driven RNAi drug discovery — $30M upfront, milestone-heavy structure. Lundbeck's bocunebart hits Phase IIb primary endpoint with 1.38-day treatmentdifference in refra...

Jun 04, 2026 | SCOTUS Backs Hikma Skinny-Label Win on Vascepa; ADC Therapeutics Crashes 50% on Death

June 04, 2026 7:43pm 10 min

SCOTUS unanimously backs Hikma's skinny-label Vascepa generic, reshaping patent defense for branded pharma. ADC Therapeutics drops 50%+ on LOTIS-5 death rate (13.2% vs 4.6%), biotech M&A crosses $106B in 2026, and Legend...

ASCO 2026 Special, Part 2 — ThClosing Days: Iza-bren Doubles Down in TNBC & Esophageal

June 03, 2026 11:38am 18 min

Part 2 of The Pharma Closeout's ASCO 2026 special covers the closing days, MondayJune 1 and Tuesday June 2 — net-new readouts plus resolution of Part 1's June 1-2 watch-list. HEADLINE: izalontamab brengitecan (iza-bren),...

ASCO 2026 Special — Comprehensive Opening Weekend: Daraxonrasib Doubles Pancreatic OS

June 01, 2026 1:54pm 27 min

ASCO 2026 comprehensive opening-weekend recap (28 readouts through Sunday, May 31). Headline: Revolution Medicines' RASolute 302 doubles overall survival in second-line pancreatic cancer (daraxonrasib, 13.2 vs 6.7months,...

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